ADRC Components

Alzheimer’s disease and the other dementias are complex multisystem disorders that impact the person at multiple levels (e.g., cognitive, physical, psychological, social) and, therefore, require an interdisciplinary approach to both research and care. The UCI Alzheimer’s Disease Research Center (ADRC) integrates clinical and basic science investigators from a variety of disciplines into a comprehensive research team that is organized into five components:

Clinical Core

 Outreach, Recruitment, and Education (ORE) Core

Neuropathology Core

Data Management and Statistics Core

Administrative Core

Creating a focal point for research on Alzheimer’s disease and related dementias at UCI, the UCI ADRC brings together investigators from Neurology, Pathology, Statistics, Neurobiology and Behavior, Molecular Biology and Biochemistry, Cognitive Sciences, Anatomy and Neurobiology, Chemistry, Geriatric Medicine, Physiology and Biophysics, and the Center for Learning and Memory.


Helps families affected by Mild Cognitive Impairment (MCI), Alzheimer's disease, or another dementia while gathering invaluable research data about the clinical presentation and progression of these cognitive disorders.
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Outreach, Recruitment, and Education
Garners community involvement in research, combats the widespread lack of knowledge about Alzheimer’s disease through a variety of education and outreach activities.
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Was it really Alzheimer’s disease? This is the most important question that the Neuropathology Component addresses upon the death of a research volunteer for the children and grandchildren who are concerned about developing dementia.
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Data Management and Statistics
Responsible for transferring our ADRC data to the National Alzheimer’s Coordinating Center which houses and makes available data from all 29 Alzheimer’s disease centers to researchers worldwide.
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Responsible for high-level planning, coordinating the five components and any research projects funded through the ADRC, attracting and nurturing the development of new investigators, and managing all ADRC operational requirements.
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