Data Management and Statistics Core

The Data Management and Statistics (DMS) Core, led by Dr. Dan Gillen, is responsible for providing efficient, comprehensive, and secure data management and analytic support for the ADRC.  The primary mission in the DMS Core is to facilitate clinical and basic science research in the area of Alzheimer’s disease.

Data Management and Statistics Component Leader, Dan Gillen, Ph.D.

Core Leader, Dan Gillen, Ph.D.

As a statistician, Dr. Gillen’s goal is “to quantify the degree of uncertainty in relationships within the data with the ultimate goal of making general statements about the aging population.”


Dan Hoang, Data Manager and Nadim Madi, Program Analyst

Identifying and applying the most appropriate statistical analyses to answer a research question is often one of the most challenging aspects of completing a study.  Hence, the ADRC makes Dr. Gillen and his team of statisticians available to consult on study design and conduct sophisticated analyses.  As Dr. Gillen explains, “Faculty and staff in the DMS Core are experts in clinical and observational methods who value collaborative science and seek long-term collaborations for advancing knowledge in the field.”

Investigator Resources

The UCI ADRC collects and maintains clinical and neuropathological data to support a variety of scientific studies.

Longitudinal clinical data from participants

  • Basic demographics
  • Medical history
  • Medications
  • Family history
  • Physical and neurological exam
  • APOE genotype
  • Consensus diagnosis
  • Comprehensive neuropsychological testing battery

Neuropathological data from participants

  • Cause of death
  • Brain weight
  • Braak staging
  • Vascular findings
  • Neuropathological diagnosis
  • Presence/absence of neuropathological features of most dementias
  • Longitudinal clinical data is available in many cases

Finally, the DMS Core is responsible for transferring our ADRC data to the National Alzheimer’s Coordinating Center which houses and makes available data from all 29 Alzheimer’s Disease Centers to researchers worldwide.

Data Management and Statistics Core Members

  • Dan Gillen, Ph.D., Core Leader
  • Maria Corrada, Sc.D., Core Investigator
  • Michael Phelan, Ph.D., Core Investigator
  • Dan Hoang, Data Manager
  • Nadim Madi, Program Analyst

For detailed information about the data, statistical, and other resources available to investigators through the UCI ADRC, visit


Helps families affected by Mild Cognitive Impairment (MCI), Alzheimer's disease, or another dementia while gathering invaluable research data about the clinical presentation and progression of these cognitive disorders.
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Education and Information
Garners community involvement in research, combats the widespread lack of knowledge about Alzheimer’s disease through a variety of education and outreach activities.
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Was it really Alzheimer’s disease? This is the most important question that the Neuropathology Component addresses upon the death of a research volunteer for the children and grandchildren who are concerned about developing dementia.
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Data Management and Statistics
Responsible for transferring our ADRC data to the National Alzheimer’s Coordinating Center which houses and makes available data from all 29 Alzheimer’s disease centers to researchers worldwide.
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Responsible for high-level planning, coordinating the five components and any research projects funded through the ADRC, attracting and nurturing the development of new investigators, and managing all ADRC operational requirements.
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