Alzheimer’s research at UCI “ramps up”

screen-shot-2016-10-03-at-9-26-54-pm“UCI MIND takes multipronged approach to finding preventions, cures in effort to avert baby-boom crisis…”










  more >

Investigational antibody treatment yields exciting though preliminary results

September 1, 2016

A paper published August 31 in Nature, describes that Biogen Idec’s candidate treatment, aducanumab, reduced amyloid-β in the brains of patients with early-stage Alzheimer’s disease. Patients receiving the highest doses of the medicine in the Phase IB trial had the largest reductions in brain amyloid and also declined the least in clinical assessments.

more >

Sept 30 Research Conference – Featured Topic: Frontotemporal Dementia

ftd image

Did you know that frontotemporal dementia (FTD) is more common than Alzheimer’s disease in people younger than 60 years old?

FTD is a cluster of progressive, degenerative brain diseases that result in significant behavior and personality changes, typically before symptoms of memory loss occur. more >

University of California announces UCI as a recipient of UC Cures for Alzheimer’s Disease award

ucal-fb-imageUC Office of the President
July 25, 2016

University of California announces UCI team, led by UCI MIND co-director Dr. Joshua Grill, as a recipient of the UC Cures for Alzheimer’s award. Read more…“Joshua Grill, associate professor in the department of psychiatry and human behavior at UC Irvine, will lead a team to study the effects of high doses of vitamin nicotinamide in reducing tau phosphorylation in patients with Alzheimer’s disease…” more >

Why women are needed in Alzheimer’s prevention studies now more than ever

mariashriver picJuly 19, 2016

UCI MIND Co-Director Dr. Joshua Grill and A4 Study Project Leader Dr. Reisa Sperling work to understand the heavy burden Alzheimer’s disease places on women– and what women can do to help today.


  more >

UCI MIND collaborates in developing potential vaccine for Alzheimer’s disease


vaccine image

July 13, 2016


Read about Professor David Cribbs’ global partnership in developing anti-amyloid-beta & anti-tau vaccines with “promise for both preventive & therapeutic approaches in AD.”

more> more >

Dr. Joshua Grill serves as expert for Alzheimer’s Prevention Registry

ask the expert“Dear Dr. Grill,

My Mom is interested in taking part in a “transparent” preclinical trial on Alzheimer’s disease. As part of the study, she would undergo Positron Emission Tomography, also called a PET scan. Because this is a transparent study, I understand she’ll receive the results of this PET scan. more >

Leslie Thompson studies point to new targets for Huntington’s disease treatments

Leslie Thompson

UCI MIND’s Leslie Thompson has worked on Huntington’s disease for over two decades, and her group’s research has revealed extensive insights into the biological underpinnings of the disease. During the week of July 15, her laboratory adds to its impressive log of discoveries. more >

CBS 2 News Increases Awareness of MCI

CBS 2 News spot features Steve and Gincy Heins, who shared their story of living with Steve’s Mild Cognitive Impairment at the 2012 Southern California Alzheimer’s Disease Regional Conference on September 21, 2012 – World Alzheimer’s Day.  As Dr. Aimee Pierce of the UCI MIND cautions, any memory or thinking difficulties that interfere with one’s everyday life should be brought to the attention of a physician and evaluated carefully. more >

KCAL 9 News Features UCI MIND

KCAL 9 News highlights research at UCI MIND which was shared at the 20th Annual Southern California Alzheimer’s Disease Conference, held on September 21st, World Alzheimer’s Day. more >