Sleep is associated with tau pathology in early Alzheimer’s disease

By January 17, 2019Community Events, In the News

Bryce Mander, PhD

Colleagues at Washington University School of Medicine published novel findings on the correlation between tau tangles, a hallmark of Alzheimer’s disease pathology, and sleep quality in people who were cognitively normal or who had mild cognitive impairment.

On ALZFORUM, UCI MIND faculty member, Dr. Bryce Mander commented, “This is an important paper because it shows for the first time how tau is related to sleep deficits. That’s going to be important in advancing our understanding of how Alzheimer’s disease pathology affects sleep.”

Dr. Mander, Assistant Professor of Psychiatry & Human Behavior at UCI, has published several important findings on the link between sleep and cognitive aging. He is currently involved in multiple collaborative projects at UCI and other academic institutions around the world. His research program aims to characterize how and when sleep interacts with Alzheimer’s disease pathology and to determine if sleep interventions can effectively promote healthy cognitive aging in older adults with or at risk for Alzheimer’s disease.

To learn more about this topic, tune in to UCI MIND’s first-ever Facebook Live video series, ASK THE DOC: Alzheimer’s Research Today. On February 1 at 9AM PST, Dr. Mander will discuss sleep and brain health and answer questions from viewers. Like @UCIrvineMIND on Facebook to be notified when we go live!