Yearly Archives

2017

Maria Shriver’s Women’s Alzheimer’s Movement Partners with UCI MIND to Launch New Women-Focused Research Initiative

By | In the News | No Comments

More than 5.5 million Americans have Alzheimer’s disease. Two-thirds of them are women. The initiative will fund critical new women-based research. ORANGE COUNTY, Calif., (December 5, 2017) — A new partnership in Orange County, California is seeking answers to an essential question affecting global health: Why do more women get Alzheimer’s disease than men? UCI MIND, the University of California at Irvine’s Institute for Memory Impairments and Neurological Disorders, has announced a new research initiative in partnership with the Women’s Alzheimer’s Movement (WAM), a non-profit organization founded by former California First Lady Maria Shriver. The initiative, based on collaborative fundraising by both…

Read More

New study estimates 47 million Americans with preclinical Alzheimer’s disease

By | In the News | No Comments

In a study published today in Alzheimer’s & Dementia, UCI MIND faculty members Drs. Claudia Kawas and Maria Corrada, and colleagues at UCLA, reported the first estimates of preclinical Alzheimer’s disease (AD) and mild cognitive impairment (MCI) prevalence in the United States. According to the study, 2.4 million Americans are living with MCI due to AD (memory and other cognitive problems that do not meet criteria for dementia), and this number is expected to more than double by 2060. Moreover, the researchers estimated about 47 million Americans have preclinical AD, the presence of amyloid accumulation and/or neurodegeneration with no symptoms of memory…

Read More

Love, Marriage, and Alzheimer’s disease

By | Commentary | No Comments

Numerous studies have shown links between lifestyle factors and risk for Alzheimer’s disease and other dementias. A new assessment of available studies by investigators at University College in London examines one lifestyle factor, marriage, and finds that people with a spouse may be at decreased risk for Alzheimer’s disease and other dementias. In contrast, widows and people who have been single their whole lives may be at 20-40% increased risk. At UCI MIND, a variety of studies have explored the implications of spousal status on Alzheimer’s disease clinical trials. In particular, we’ve shown that people with Alzheimer’s who lack a…

Read More

Perspectives on amyloid PET imaging

By | Commentary, In the News | No Comments

A new study published in JAMA Neurology explored participants’ perspectives on receiving amyloid PET scan results as part of an Alzheimer’s disease prevention clinical trial, the A4 study.  Participants at UCI MIND contributed to this important research, led by investigators at the University of Pennsylvania (read more about the study here). Amyloid PET is a biomarker test that could someday be used to identify people at increased risk for Alzheimer’s disease who may benefit from preventative or disease-delaying treatments. Biomarker testing such as amyloid PET is being used more and more in the research setting to identify participants appropriate for Alzheimer’s disease…

Read More

New UCI MIND animal model grant continues to draw attention

By | In the News | No Comments

UCI MIND co-director Frank LaFerla and Drs. Andrea Tenner, Kim Green, Grant MacGregor, Marcelo Wood, and David Baglietto-Vargas were awarded an $11.35 million grant from the National Institutes of Health to create the next generation of mouse models to study Alzheimer’s disease. The news released by UCI on October 9 continues to draw local media attention, featured in the LA Times/Daily Pilot and Newport Beach Patch this morning. UCI MIND is already home to the discovery of the first ever mouse model to develop both amyloid plaques and neurofibrillary tangles, the two hallmark pathologies of Alzheimer’s disease. Created by Dr….

Read More