UCI to take part in clinical trial of drug for critically ill COVID-19 patients

By Commentary, COVID-19, In the News

  UCI Health will initiate a clinical study of a drug to treat critically ill COVID-19 patients who face a high mortality rate because of acute inflammation that fills their lungs with fluid, a grave condition that even mechanical ventilation cannot improve. Aviptadil, which has a 20-year history of use in human clinical trials for lung ailments, will be employed in a phase 2b/3 clinical study of COVID-19 patients suffering from acute respiratory distress syndrome, a primary cause of coronavirus-induced death. Read more here > Related posts: Campus labs making sample-preserving fluid for COVID-19 test kits … UCI and UCI…

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Research team awarded $3.8 million to study molecular changes in the brain caused by Alzheimer’s disease

By Carousel Slider, Commentary, In the News

Irvine, CA – May 12, 2020 – A team of researchers from the University of California, Irvine and San Diego have been awarded $3.8 million by the National Institute on Aging to conduct an epigenomic analysis of neural circuits in the brain. By revealing molecular changes that occur during the course of Alzheimer’s disease (AD), the team hopes to identify new therapeutic targets and molecular biomarkers for early detection and better treatment. The interdisciplinary research team is led by multiple principal investigators, including Xiangmin Xu, PhD, a professor of anatomy and neurobiology and director of the Center for Neural Circuit…

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Racing to deliver COVID-19 testing

By Commentary, Community Events, In the News

  Read how through the efforts of the UC Irvine Health team, under the leadership of UCI MIND Faculty Member, Dr. Edwin Monuki, the medical center became the first hospital in Orange County to provide in-house COVID-19 testing on March 19 – more than two weeks ahead of schedule. http://www.ucihealth.org/…/racing-to-deliver-covid19-testing Dr. Monuki recently commented on antibody testing for the UCI MIND Blog and will participate in a virtual panel discussion tonight, May 14 at 7 PM PST. Click HERE to register. Related posts: VIDEO: “Is there a blood test for Alzheimer’s?” with Dr. Mark Mapstone … Dementia developments … VIDEO: UCI…

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New partnership will give nursing home staff extra training to prevent coronavirus spread

By Commentary, COVID-19, In the News

CalOptima, which provides health insurance to Orange County’s low-income residents, announced on Friday, May 8, it is working with UC Irvine and the county Health Care Agency to provide intensive training on infection control to staff at 12 nursing homes. … Dr. Susan Huang, who teaches about infectious diseases at UC Irvine, is working with researchers and clinicians to develop the tools and training, and will measure their effectiveness with diagnostic and antibody testing. Related posts: UCI researchers will test former Ebola drug as part of coronavirus clinical trial … Join the CA Dept. of Aging on April 22 for…

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APOE4 carriers show early breakdown to blood-brain barrier, before cognitive impairment

By Commentary, In the News

Contributed by Daniel Nation, PhD, UCI MIND Faculty Member, Associate Professor of Psychological Science at UCI   APOE4 is the strongest known genetic risk factor for Alzheimer’s disease, the most common cause of dementia characterized by the accumulation of amyloid plaques and tau tangles. Although the predominant view has been that APOE4 conveys risk for Alzheimer’s dementia primarily through its effects on amyloid levels, prior work has also shown that APOE4 has adverse effects on the blood vessels of the brain.   In a recent study published in Nature, colleagues at University of Southern California and I demonstrated that APOE4…

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Virtual COVID-19 Panel: UCI Experts Discuss the Pandemic

By Commentary, Community Events, COVID-19

The Center for Biotechnology and Global Health Policy and the Sue & Bill Gross Stem Cell Research Center have partnered to host a virtual panel of experts discussing COVID-19. The event takes place Thursday, May 14, from 7 to 8 p.m.  Four experts, including UCI MIND faculty member Dr. Ed Monuki, will address the COVID-19 pandemic. Dr. Monuki recently blogged about the state of antibody testing. Hear more on this topic at the virtual panel. Register here. It will be streamed on Facebook at facebook.com/UCIStemCell and on YouTube at https://youtu.be/Pau-eWPE0RY. For further information, contact Judy Baek at Judy.baek@uci.edu Related posts:…

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Caring for a loved one with dementia during COVID-19

By Commentary, COVID-19

California’s stay-at-home order has been especially tough for one caregiver population: Family members caring for someone who has dementia. Because of the novel coronavirus, adult daycare centers are closed temporarily and home services have been put on hold, cutting off critical support systems for this group. Here are a few tips from UCI Health for anyone now caring for a family member with dementia, provided by Jung-Ah Lee, PhD, an associate professor at the UCI Sue & Bill Gross School of Nursing: Read the full article here > Related posts: COVID-19: Anatomy of a Scam … Lessons in “Transition” Contributed by…

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UCI Launches ASSIST Program for Isolated Seniors

By Commentary, Community Events, COVID-19

UCI has launched the ASSIST Program – Assisting & Serving Socially Isolated Seniors via Telephone.  UCI medical and nursing students who have been mobilized received the program training, and are ready to be paired with older adult participants who would like to receive regular check-ins via telephone just to chat and/or to receive referrals to community resources during this difficult time while they are self-isolating. The flyer is linked here and provided below. If interested, please call: (714) 497-0315.   Related posts: VIDEO: Message from our Associate Director of Education, Chelsea Cox … Alzheimer’s disease, clinical trials, & COVID-19: Q&A…

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Stuck at home? Help UCI Researchers Cure Diseases

By Commentary, COVID-19, In the News

During this time of uncertainty, communities, businesses and families are being impacted like never before. People are also coming together to help others in unprecedented ways. And while we all are spending more and more time at home, many of us are looking for ways to strengthen our communities while maintaining the current health and safety recommendations from the CDC. I’d like to invite you and your families to make a real difference without leaving your home or opening your wallet. I’m an OC Mom and researcher at UCI MIND. We are seeking volunteers to sign up for our “Consent-to-Contact”…

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Minorities are disproportionately dying from COVID-19

By Commentary, COVID-19

Contributed by Christian Salazar, PhD, UCI MIND Project Scientist The COVID-19 pandemic has had a devastating impact on families all across our country, with 70,000 reported deaths to date. Early in the pandemic the data had suggested that African Americans were being admitted to the hospital and dying in disproportionate numbers. In fact, an analysis by the Washington Post revealed that coronavirus death rates were about six times higher in black majority counties than in white majority counties. More recent data also showed that Latinos and Indigenous groups like the Navajo people were dying in excess numbers. What could explain…

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