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Hope Dies Last – OC World Documentary

By Carousel Slider, Commentary, In the News

Hope Dies Last – Alzheimer’s: A Journey of Lost Memories, comes out TODAY at 3:30pm! Check out this clip of UCI MIND Director, Joshua Grill, Ph.D. discussing the impacts of Alzheimer’s disease on Orange County residents. Tune in today at 3:30pm on KDOCTV for the full program! Related posts: New genetically modified mouse model mimics multiple aspects of human Alzheimer’s disease NIA-supported scientists have developed a new mouse model that produces a form of the human beta-amyloid protein, a hallmark of Alzheimer’s disease. An important research tool, mouse models enable the exploration of genetic, environmental, and behavioral aspects of Alzheimer’s,…

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Spotlight on Care has over 3,000 downloads!

By Commentary, In the News

Thank you to our listeners! Catch up on the latest episodes of our podcast for caregivers, Spotlight on Care: mind.uci.edu/podcast Related posts: New Mouse Model Provides 1st Platform to Study Late-Onset Alzheimer’s UCI School of Biological Sciences Dean Frank LaFerla is co-senior author of a study involving a new genetically engineered mouse model that, unlike its predecessors, is based on the most common form of Alzheimer’s disease. This could help lead to major strides in the fight to end this deadly disease!… Place Your Order for Free At-Home COVID-19 Tests Residential households in the U.S. can order one set of…

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Report on Aging in Orange County 2022

By Commentary, In the News

Contributed by Orange County Aging Services Collaborative: We are excited to announce the release of the Report on Aging in Orange County 2022! This report maps the system of senior support and data available in four key areas: disability, the digital divide, food insecurity, and social isolation.Everyone is invited to read the report and are encouraged to share with your networks. Report on Older Adults in Orange County: 2022 Report on Aging in Orange County 2022 Related posts: UCI Takes a Unique Approach to Researching Orange County’s Third-Leading Cause of Death … UCI team uncovers key brain mechanisms for organizing memories in time…

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Hope Dies Last – Alzheimer’s: A Journey of Lost Memories

By Carousel Slider, Commentary, Community Events, In the News

Don’t miss this upcoming documentary filmed by OCWorld, featuring Director Dr. Joshua Grill – Tune in this Sunday on KDOCTV at 3:30pm! Contributed by OCWorld: “Tune in THIS SUNDAY on KDOCTV at 3:30pm for the premier of our final installment of our first season. This is Hope Dies Last – Alzheimer’s: A Journey of Lost Memories. This short documentary explores the impacts of Alzheimer’s disease in Orange County, a growing epicenter for the disease. Featuring insights on the disease from experts like Dr. Joshua Grill from UCI MIND and Deborah Levy, Executive Director of the Alzheimer’s Association OC Chapter. Related…

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Older Americans Month (OAM) 2022

By Commentary, Community Events, In the News

We’re celebrating #OlderAmericansMonth (OAM) this month! This year, our theme is Age My Way. We’re focusing on how older adults can plan, participate, and connect in ways they choose while aging in place, living independently in their communities for as long as possible. Find OAM resources at Visit http://ow.ly/LB2L50IVOO0 Related posts: Michelle Nuño, PhD reflects on CTAD 2021 Cognitive assessments are a crucial part of Alzheimer’s disease studies as these help track cognitive decline; however, these assessments may be subject to a practice effect, an improvement in scores due to familiarity with the assessment. Practice effects can mask cognitive decline,…

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Cell therapy: a new frontier in Parkinson’s disease

By Carousel Slider, Commentary, In the News

After decades of research into the causes and treatment of Parkinson’s disease, UCI Health neurologist Dr. Claire Henchcliffe is hopeful that a new cell therapy can finally bring meaningful relief to patients with the progressive neurodegenerative movement disorder. A national expert on Parkinson’s disease, she is one of a small group of U.S. researchers conducting a first-in-human clinical trial of transplanted stem cells engineered to replace dopamine-producing neurons that are destroyed by the debilitating and incurable condition. As the brain loses its ability to produce the potent neurotransmitting chemical, that leads to the tremors, stiffness, slowness and lack of coordination seen in Parkinson’s patients. The…

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The Collaborative Approach for Asian Americans and Pacific Islanders Research and Education (CARE)

By Carousel Slider, Commentary, In the News

The Collaborative Approach for Asian Americans and Pacific Islanders Research and Education (CARE): A recruitment registry for Alzheimer’s disease and related dementias, aging, and caregiver-related research Related posts: AD Biomarkers & Preclinical Diagnostics Report Now Available On June 28–29, 2021, the National Academies of Sciences, Engineering, and Medicine held a virtual workshop, “Behavioral and Social Research and Clinical Practice Implications of Biomarkers and Other Preclinical Diagnostics of Alzheimer’s Disease (AD) and AD-Related Dementias” (AD/ADRD). UCI MIND Director Joshua Grill was an invited participant in this meeting,… New Preventive Vaccine for Alzheimer’s Disease Gets Grant eturbonews: The Institute for Molecular Medicine…

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Visit-to-Visit Blood Pressure Variability and CSF Alzheimer Disease Biomarkers in Cognitively Unimpaired and Mildly Impaired Older Adults

By Carousel Slider, Commentary, In the News

Blood pressure variability is an emerging risk factor for cognitive decline and dementia, but mechanisms remain unclear. The current study examined whether visit-to-visit blood pressure variability is related to CSF Alzheimer’s disease biomarker levels over time, and whether associations differed by APOE ϵ4 carrier status. Related posts: Determining if Dementia Is Uniquely Human Discover Magazine: Aging dogs can develop canine cognitive dysfunction (CCD), sometimes known as “doggie dementia.” The brains of dogs with CCD show only amyloid beta plaques, not tau tangles, but their symptoms are similar to the symptoms of dementia in humans, explains Elizabeth Head, [professor of medicine and]…

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Join our team! Applications are now live for the Director of Scientific Communications

By Commentary

Join our team! Applications are now live for the Director of Scientific Communications. The University of California, Irvine’s Institute for Memory Impairments and Neurological Disorders (UCI MIND) has an opportunity for a Project Scientist. The mission of UCI MIND is to engage in cutting edge, interdisciplinary research designed to discover the basic mechanisms of neurodegeneration and brain aging, characterize the transition from normal aging to Alzheimer’s disease, and develop new treatments to slow or eliminate cognitive impairment resulting from any etiology. Critical to this mission are dissemination of research findings to the community for the purpose of increasing public confidence…

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UCI Generates Preliminary Evidence of a Gene Mutation That May Reduce Risk of Alzheimer’s Disease

By Carousel Slider, Commentary, In the News

Image Courtesy: AARP Through new developments in Alzheimer’s research, UCI scientists have uncovered evidence of P522R, a particular gene mutation that may aid in minimizing the risk of developing Alzheimer’s disease. Alzheimer’s disease is a progressive disorder that slowly deteriorates memory and thinking skills in the brain, eventually leading to a loss in the ability to complete simple tasks such as  facilitating a conversation or responding to a stimulus in the environment. With the discovery of the disease in 1906 by Dr. Alois Alzheimer, its causes today are focused on two suspects: plaques and tangles in proteins. Beta-amyloid, fragments of…

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