Days 3-4 at #AAIC19 included more impressive poster presentations from UCI MIND researchers AND prestigious poster awards received by TWO postdoctoral trainees 👏 Congrats to Drs. Lindsay Hohsfield (Kim Green lab) & Davis Woodworth (Ahmad Sajjadi lab)!Postdoctoral trainee in Dr. Kim Green's lab, Dr. Lindsay Hohsfield, won the Basic & Translational Science Poster Competition at #AAIC19 for her innovative research on the association between microglia and tau pathology in Alzheimer's disease.Postdoctoral trainee with Dr. Ahmad Sajjadi, Dr. Davis Woodworth, won the Diagnosis & Prognosis Poster Competition at #AAIC19 for his innovative research into the utility of MRI detection of atrophy…
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Day 2 of #AAIC19 included lectures on sleep and Alzheimer's disease from Drs. Ruth Benca and Bryce Mander, opportunities for collaboration, and rich discussion over poster presentations from numerous UCI MIND faculty and trainees.Dr. Ruth Benca, UCI Professor & Chair of Psychiatry & Human Behavior, was invited to deliver a plenary lecture among the world's experts in Alzheimer's disease research. #AAIC19Dr. Ruth Benca presented a plenary lecture on sleep and Alzheimer's disease to over 5,000 international investigators at #AAIC19ASK! Open Q&A session with Dr. Ruth Benca after her plenary lecture #AAIC19Dr. Bryce Mander presented on using local slow-wave measured during…
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This week, many UCI MIND researchers are sharing their work and collaborating with researchers across the globe at the Alzheimer's Association International Conference in LA! Check out some photos from Day 1 and stay tuned for updates.#AAIC2019 in LA!Davis Woodworth, a postdoctoral trainee working with Dr. Ahmad Sajjadi presented a poster on using MRI to detect atrophy in hippocampal sclerosis. #AAIC2019UCI MIND project scientist and epidemiologist, Christian Salazar, presented a poster on racial and ethnic differences in willingness to be contacted about research studies. #AAIC2019Dr. Claudia Kawas was asked to present and participate on an esteemed panel discussion of limbic-predominant…
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Facebook Live Series - ASK THE DOC: Alzheimer's Research Today! This monthly series features short talks and Q&A with experts from the University of California, Irvine Institute for Memory Impairments and Neurological Disorders (UCI MIND), 1 of 32 congressionally designated Alzheimer’s Disease Research Centers in the nation. Join UCI MIND on Facebook (@UCIrvineMIND) the first Friday of every month from 9:00-9:30 AM PST to learn about advances in research to improve Alzheimer’s disease diagnosis, treatment, and prevention. Episode 6: "What medications can I take to prevent or treat Alzheimer's?" This month, we're joined by Steven Tam, MD. Dr. Tam is…
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The Global Council on Brain Health (GCBH), in partnership with AARP, recently released an extensive report reviewing the current evidence on brain health supplements. AARP formed the GCBH by bringing together an independent group of scientists, physicians, researchers, and other experts. Click here to learn more about these specialists. The GCBH found that there was a lack of evidence for effectiveness, concerns about false claims in marketing, and uncertainty of the possible risks of brain health supplements, since they are not required to be reviewed for purity, safety, and efficacy. The GCBH concluded that no endorsement could be made for…
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Contributed by Joshua Grill, PhD The field of Alzheimer’s disease drug development received more troubling news yesterday, when the leaders of the GENERATION program halted their prevention clinical trials of a drug aiming to prevent the formation of the beta amyloid protein in people at risk to get Alzheimer’s disease. The GENERATION program is led by investigators at Banner Alzheimer’s Institute and is an important study in people at increased genetic risk to someday develop Alzheimer’s disease, based on the apolipoprotein E (APOE) gene. The trials were stopped because preliminary results indicated that the drug under study, CNP520 (being developed…
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Tune in this Friday, July 12 @ 9AM for the next episode of our monthly Facebook LIVE series, "What medications can I take to prevent or treat Alzheimer's?" This month, we're joined by Steven Tam, MD. Dr. Tam is an Assistant Clinical Professor of Medicine and a Geriatrician at UC Irvine and recognized as a Physician of Excellence by the Orange County Medical Association. He specializes in geriatric neurology and serves as principal investigator for two Alzheimer's disease clinical trials at UCI MIND. To attend LIVE and ask Dr. Tam YOUR questions, login to Facebook this Friday morning and search @UCIrvineMIND to view the video…
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Contributed by Joshua Grill, PhD, Director of UCI MIND A recent report from The Economist concludes that three neurological disorders — migraine, multiple sclerosis, and Alzheimer’s disease — are impacting workplace productivity. Notably, all three conditions disproportionately affect women. While it is now clear that Alzheimer’s disease begins decades prior to diagnosis, the larger impact on the global economy results from the growing number of workers who are trying to balance employment as well as caregiving for a parent with the disease. More than 16 million Americans are unpaid caregivers for someone with Alzheimer’s disease and the most common caregiver is…
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Contributed by Carl W. Cotman, PhD and Nicole C. Berchtold, PhD It is increasingly recognized that exercise builds brain health. At a fundamental level, brain health and function depend on the expression of the brain’s genes, the building blocks of cells. In a recent paper that appeared in the journal “Neurobiology of Aging” (2019), Drs. Carl Cotman, Nicole Berchtold and coworkers demonstrated that in the brains of healthy older people, exercise reprograms gene expression patterns to a more youthful state, even in cognitively normal people (75-100 yrs old). Genes that were particularly targeted are those that boost cellular energy production and build…
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