Category

Carousel Slider

NPR asks founding director to comment on exercise study

By | Carousel Slider, In the News | No Comments

A study was recently published in the journal Neurology about physical activity’s relation to Alzheimer’s disease and cognition in older adults. NPR asked UCI MIND founding director Dr. Carl Cotman to comment on this impressive study, noting that exercise might “‘offset the ill effects of brain degeneration.’ He adds that lifestyle interventions such as an increase in physical activity and movement can be powerful even in the presence of disease.” Click here to read the article > Dr. Cotman is leading a national clinical trial of exercise at UCI MIND. The trial aims to evaluate whether 18 months of moderate to…

Read More

Dr. Ira Lott, Director of UCI MIND Down Syndrome Program, featured in OC Business Journal

By | Carousel Slider, In the News | No Comments

Dr. Ira Lott, Director of the UCI MIND Down Syndrome Program, discussed the connection between Down syndrome and Alzheimer’s disease with the Orange County Business Journal this week.  Dr. Lott and his team conduct critical research studies with volunteer participants to improve understanding of brain aging and dementia in Down syndrome. Click here to read the article > To learn more about studies in Down syndrome and Alzheimer’s disease, click here >

Read More

Novel genetics research opens door to potential new therapies for dementia

By | Carousel Slider, In the News | No Comments

UCI MIND faculty member, Dr. Vivek Swarup, and colleagues at UCLA, Takeda Pharmaceutical Co. Ltd. in Japan, Emory University School of Medicine, Harvard Medical School, and the Perelman School of Medicine at the University of Pennsylvania, published novel findings yesterday in Nature Medicine on two major groups of genes associated  with Alzheimer’s disease and frontotemporal dementia and unraveled a novel microRNA, miR-203, as a master regulator of neuronal death. In human cell cultures containing AD-associated mutations, the researchers showed that certain experimental drugs altered the loss of brain cells associated with neurodegenerative disease. Dr. Swarup says, “I’m hopeful these important findings will bring us one step closer to effective new treatments…

Read More

Dr. Blurton-Jones awarded grant to identify potential treatments for Alzheimer’s disease

By | Carousel Slider, In the News | No Comments

UCI MIND faculty member Dr. Mathew Blurton-Jones was awarded a $500,000 grant from Orange County Community Foundation to test 1200+ FDA-approved compounds for effectiveness in Alzheimer’s disease treatment. His lab seeks to find the top 20 genes and drugs that safely prevent brain damage caused by microglia, which are critical immune cells in the brain that ‘prune’ unnecessary neuronal connections, or synapses. In the brains of people with Alzheimer’s disease, damage can be caused by microglia ‘overpruning’ synapses, leading to loss of necessary connections. UCI News reports that Dr. Blurton-Jones and his team are “grateful to be the recipients of this…

Read More

UCI MIND selected as Center of Excellence to conduct clinical trials in Down Syndrome and Alzheimer’s disease

By | Carousel Slider, In the News | No Comments

UCI MIND faculty member, Dr. Ira Lott, is one of the world’s leading experts in unraveling the link between Down syndrome and Alzheimer’s disease (Learn more in the Winter 2016 issue of MIND Matters). His team has been selected as a Center of Excellence for the new Down Syndrome Clinical Trial Network (DS-CTN) launched by LuMIND, a Down syndrome research foundation. As part of this important network, Dr. Lott and his team will receive funding to conduct clinical trials of promising therapies for participants with Down syndrome, at risk for Alzheimer’s disease. To learn more about the initiative and the…

Read More