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Commentary

A personal note from UCI MIND neurologist, Dr. Ahmad Sajjadi

By Commentary, COVID-19

Contributed by Ahmad Sajjadi, MD, PhD, Assistant Professor of Neurology The ways in which the COVID-19 pandemic has changed our lives are so profound that I fully expect us to, at least in our own heads, divide our life events to pre- and post-pandemic. I cannot think of a similar example in my life that affected every single aspect of my daily living. Of course, like others, I have developed strict rituals for disinfecting myself and everything I touch, and it takes me about 10 minutes to enter my house from a shopping trip! Negatives aside, it has also been…

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Dr. Mark Mapstone comments for The New York Times

By Carousel Slider, Commentary, In the News

Stalked by the Fear That Dementia Is Stalking You The New York Times (Kaiser Health News) – Feb. 20, 2020 I spoke to half a dozen experts, and none was in favor of genetic testing, except in unusual circumstances. “Having the APOE4 allele does not mean you’ll get Alzheimer’s disease. Plenty of people with Alzheimer’s don’t have the allele,” said Mark Mapstone, a professor of neurology at the University of California, Irvine. “And conversely, plenty of people with the allele never develop Alzheimer’s.” [Subscription required: LINK to article]

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Revived UCI Sleep Center Focuses on Mental Issues

By Carousel Slider, Commentary, In the News

Orange County Business Journal – Feb. 17, 2020 Dr. Ruth Benca, who is chair of the Psychiatry and Human Behavior School of Medicine at the University of California, Irvine in 2018 restarted the UCI sleep center. She’s designed a new, 6,000-square foot facility in Newport Beach … and has recruited doctors from a variety of fields, such as Dr. Kevin Im, who won a 2014 national award for a sleep study, Dr. Rami Khayat, the center’s medical director and expert on the effects of sleep apnea on cardiovascular diseases, and Dr. Behrouz Jafari, an expert in pulmonology. “We’ve built this…

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From Postdocs to PI’s: Training Scientists For Success

By Commentary, In the News

Faculty members Mathew Blurton-Jones, PhD, Kim Green, PhD, and Masashi Kitazawa, PhD, are principal investigators (PI) of productive, independent laboratories at UCI MIND all aiming to target the underlying cause of and develop effective treatments for Alzheimer’s disease (AD) and related disorders. How did they get to where they are now? After graduate school in 2003, they came together from different backgrounds to train with renowned scientist, Frank LaFerla, PhD, who continues to run a successful laboratory of his own at UCI MIND.   Blurton-Jones, Green, and Kitazawa reflect on their training experience and what they believe to be their…

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Why I Support UCI MIND

By Commentary, In the News

Contributed by Keith Swayne, UCI MIND Leadership Council It is humbling to be recognized as Philanthropist of the Year, particularly when I think about the many individuals who are working to make a difference in the world. The OC National Philanthropy Day event brought together Orange County philanthropists and non-profit organizations to celebrate our shared vision of improving our community. This is what drives me. I wish to use my voice to connect people and organizations to achieve more and help others. I have strived to do this over the last five years with my involvement with UCI MIND. Alzheimer’s…

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Public Perception of Dementia Risk and Risk Reduction

By Commentary, Community Events

Contributed by Chelsea Cox, MPH, MSW, Associate Director of Education In a recent study, researchers at the University of Michigan analyzed survey responses from over 1,000 adults age 50 to 64 to learn about their perceived risk for developing dementia and any actions they take to reduce their own risk. The study found that more than half of respondents believed they were not likely to develop dementia, with this outlook being more common in non-Hispanic blacks who are, in fact, at a greater risk of developing dementia than non-Hispanic whites. The vast majority of respondents reported having never discussed risk…

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First-of-its-kind study links the sleeping brain to toxin-clearing

By Commentary, In the News

Contributed by Bryce Mander, PhD A new landmark study from researchers in Boston was published in Science this month. This study linked human brain waves during deep sleep, called “slow waves,” with the pulsating flow of cerebrospinal fluid (CSF) through the brain.   This study is important because it is the first to directly link sleeping brain waves with a mechanism thought to clear the brain of metabolic waste and toxins, called the “glymphatic system.” Prior studies in rodents indicate that the glymphatic system actively clears Alzheimer’s disease pathology, as well as other toxins and waste products, from the brain….

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Another hopeful outcome for Alzheimer’s treatment

By Commentary, In the News

Contributed by David Sultzer, MD, Professor of Psychiatry & Human Behavior This past weekend, China’s regulatory agency conditionally approved sodium oligomannate for the treatment of mild to moderate Alzheimer’s disease.  The approval was based on results from a 9-month treatment study of 818 people, and is the first approval globally of an Alzheimer’s drug in 16 years. Oligomannate (GV-971) is a plant-based complex sugar derived from ocean seaweed. It’s thought to adjust the microbiome in the GI tract, thereby tweaking amino acid levels in the body and reducing the toxic effects of brain inflammation that contribute to Alzheimer’s disease.  Results from…

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Learn about the 30th annual conference panel

By Commentary, Community Events

Learn about the 30th annual conference panel in today’s #SpeakerSpotlight: Moderated by UCI MIND Director Joshua Grill, a diverse panel of stakeholders will provide their unique perspective on challenges and successes in Alzheimer’s disease research and what they anticipate for the future of the field. Panelists include a research participant, a family caregiver, and clinicians and scientists from University of California, Irvine: Dr. Lisa Gibbs is a Clinical Professor of Family Medicine and Chief of the Division of Geriatric Medicine and Gerontology at UCI School of Medicine. She also serves as Medical Director of the UC Irvine HealthSeniorHealth Center in Orange…

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