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Dr. Cotman Receives Honorary Doctorate from McGill University

By In the News

Congratulations to Dr. Carl Cotman, professor of Neurology, Neurobiology and Behavior, and Biomedical Engineering at the University of California, Irvine who received an honorary doctorate from McGill University in Montreal as part of its 2012 commencement exercises.  Dr. Cotman, who founded the UCI Institute for Memory Impairments and Neurological Disorders (UCI MIND), was awarded a Doctor of Science, honoris causa, in recognition of the many contributions he has made to our understanding of Alzheimer’s disease and other age-related cognitive disorders throughout his distinguished career.  He joins a select group of faculty to receive this honor. In his invited convocation address,…

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Registration Open for 20th Annual Alzheimer’s Disease Research Conference

By In the News

Register Now . . . for the 20thAnnual Southern California Alzheimer’s Disease Conference, to be held on World Alzheimer’s Day, Friday, September 21, 2012 at the Hilton Orange County/Costa Mesa. Joining worldwide efforts to increase understanding of Alzheimer’s disease and other forms of dementia, the Institute for Memory Impairments and Neurological Disorders at the University of California, Irvine (UCI MIND) and its community partners, the Alzheimer’s Association of Orange County and Alzheimer’s Family Services Center, are bringing together experts from across the country to address the topic, Beyond Memory: The Behavioral and Psychiatric Symptoms of Dementia. Today, over 5.4 million…

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Family Education Series Available Online

By In the News

The Family Education Series, taught by Dr. Malcolm Dick, Senior Neuropsychologist at the UCI MIND Memory Assessment and Research Center, and Dr. Cordula Dick-Muehlke, Director of Education at UCI MIND, is now available online.  Workshops available for viewing are Alzheimer’s Disease and Other Dementias: What Does the Diagnosis Mean? and Alzheimer’s Disease: Behavior and Communication Strategies.   View the workshops online or attend the 2013 series in person.     For more information or to pre-register, call (949) 824-2382.

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Exercise and Diet in Alzheimer’s Disease

By In the News

Dr. Carl Cotman, founding director of the UCI Institute for Memory Impairments and Neurological Disorders, explains how regular exercise and a diet rich in antioxidants support brain health. This video is part of the “The Alzheimer’s Project,” a presentation of HBO Documentary Films and the National Institute on Aging at the National Institutes of Health in association with the Alzheimer’s Association, the Fidelity® Charitable Gift Fund and Geoffrey Beene Gives Back® Alzheimer’s Initiative.

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Dr. Frank LaFerla Featured by SeniorCareHomes.com

By In the News

Dr. Frank LaFerla serves as Chief Alzheimer’s Research Expert for SeniorCareHomes.com.  He shares the urgent need to advance research about Alzheimer’s disease and the efforts of UCI MIND to ensure that memories last a lifetime for future generations.  Today, 5.4 million Americans have Alzheimer’s disease and a new case of develops in the United States every 68 seconds.  Without effective treatment and prevention strategies, the number of Americans affected by Alzheimer’s disease will grow to at least 16 million by 2050, with the cost of care bankrupting our society.

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David Cribbs, Ph.D. Appointed to VA Scientific Merit Review Board

By In the News

Dr. David Cribbs, Associate Director of UCI MIND and Professor in Residence in the Department of Neurology, has been appointed to the Department of Veterans Affairs Joint Biomedical Laboratory Research  and Development (BLR&D) and Clinical Science Research and Development (CSR&D) Services Scientific Merit Review Board. As a board member, Dr. Cribbs will provide advice on the scientific quality, budget, safety and mission relevance of investigator-initiated research proposals submitted for intramural funding at the VA.  Funding is available for studies that prove both scientifically meritorious and relevant to the health of veterans. The board fulfills its mission through a series of expert…

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Inspiring Others to Join the Fight Against Alzheimer’s Disease

By In the News

An inspiration – that’s what Nancy Jenkins has been all her life – and continues to be even in the face of Alzheimer’s disease, which is gradually destroying her memory and thinking abilities.  These days, Nancy is inspiring others, even her husband, Larry, to follow her footsteps in advancing research for Alzheimer’s disease.  An active participant in the longitudinal research program at the University of California Irvine Institute for Memory Impairments and Neurological Disorders (UCI MIND) for the past 8 years, Nancy is allowing doctors to follow the progression of her disease annually and has agreed to donate her brain…

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UCI MIND Launches Outreach to Chinese Americans

By In the News

An overflow crowd of 160 Chinese Americans attended the UC Institute for Memory Impairments and Neurological Disorder’s (UCI MIND) first workshop on memory loss targeting this growing ethnic community.  Offered with translation, Memory Loss: Should I Be Concerned? was presented at the Irvine Chinese School on May 4, 2012 by UCI MIND experts, Dr. Malcolm Dick, Senior Neuropsychologist, and Dr. Cordula Dick-Muehlke, Director of Education, with translation support from Florence Huang, M.S.G., Community Liaison. Located in the heart of Irvine, UCI MIND is serving its local community by reaching out to Asians, who represent 39.2% of the city’s population, up…

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Any Kind of Physical Activity Protects the Oldest Old from Alzheimer’s Disease

By In the News

Staying physically active is critical for brain health, but you don’t necessarily have to break a sweat exercising to protect yourself from developing Alzheimer’s disease.   Among the oldest old, those who were the most physically active, whether through routine activities like housework and gardening or traditional exercise, had 2.3 times less risk of developing Alzheimer’s disease than those who were the least physically active, according to a study just published in the April 24, 2012 issue of Neurology. Dr. A. S. Buchman, lead author, and his colleagues at the Rush Alzheimer’s Disease Center, measured level of physical activity among 716…

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Time of Your Life raises $100,000 for Alzheimer’s Research at UCI MIND

By In the News

More than 500 guests stepped back in time to the 1960s at the Time of Your Life fundraiser, held at the Center Club in Costa Mesa on March 10, 2012.  The benefit, in support of Alzheimer’s research at UCI MIND, was led by Jacqueline DuPont, Ph.D., Irvine Cottages, and her husband, Marc Carlson, and fellow co-chair, Linda Young.  The threesome had volunteered for two previous successful UCI MIND fundraisers.  They gathered their team of loyal volunteers to serve on this year’s committee to produce a truly unique event.  You had to be there! With the generous support and underwriting of…

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Researching Ways to Make Memories Last a Lifetime

By In the News

Every 4 seconds another person in the world develops Alzheimer’s disease, a statistic released by the World Health Organization in its 2012 report, Dementia, A Public Health Priority, on April 11 and highlighted by Dr. Frank LaFerla, Director of the UC Irvine Institute for Memory Impairments and Neurological Disorders (UCI MIND), that same evening in his presentation, Researching Ways to Make Memories Last A Lifetime, at the 18th UCI Distinguished Lecture Series on Brain, Learning and Memory, co-hosted by the UCI Center for Neurobiology, Learning and Memory and UCI MIND. Speaking to an audience of more than 500, Dr. LaFerla…

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A Night at Sardi’s Features Dr. Frank LaFerla

By In the News

Dr. Frank LaFerla , Director of UCI MIND, addressed the 1,000+ prominent political and entertainment industry leaders – in addition to celebrities – who gathered on March 21, 2012, at the Beverly Hilton to recognize advances in the fight against Alzheimer’s disease and rally around the growing movement to end the disease.  This annual Alzheimer’s Association gala has raised over $19 million since its inception to advance cutting-edge research, increase awareness, and address the needs of Americans living with the disease and their caregivers. In his brief address, Dr. LaFerla reminded the audience that the price is just too high…

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More Evidence that Omega-3 Fatty Acids Support Brain Health

By In the News

A study published in the February 28 issue of the journal Neurology provides more evidence that high dietary consumption of omega-3 fatty acids, found in fish such as salmon and tuna, may protect the brain against cognitive impairment. The research team, led by Dr. Zaldy S. Tan, found that healthy older adults 58-76 (m = 67) with the lowest  red blood cell (RBC) levels of the omega-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) had “older” brains than their peers as well as a vascular pattern of cognitive impairment.  Researchers examined the relationship of RBC fatty acid levels…

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Mild Cognitive Impairment and Alzheimer’s Disease – Video

By In the News

Learn about Mild Cognitive Impairment, Alzheimer’s disease, and ways to support research at UCI MIND Is dementia the same as Alzheimer’s disease?  Dr. Cordula Dick-Muehlke, Director of Education at UCI MIND, answers this common question and describes Mild Cognitive Impairment, the transitional stage between normal aging and dementia. In January 2012, UCI MIND was awarded a $25,000 grant by the S. L. Gimbel Foundation in support of Memory Screening and Education to Advance Alzheimer’s Disease Research.   Funding will enable UCI MIND to educate the community about memory loss, Alzheimer’s disease and other dementias as well as opportunities to participate in…

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Cancer drug rapidly clears amyloid plaques

By In the News

Researchers at Case Western Reserve University School of Medicine have demonstrated that bexarotene, an FDA-approved drug for the  treatment of skin cancer, dramatically and rapidly clears amyloid plaques from the brains of mice bred with Alzheimer’s disease.  Led by Gary Landreth, Ph.D.,  the study just published on line in Science Express, found that bexarotene not only enhanced clearance of beta amyloid, an abnormal protein associated with Alzheimer’s disease, but also improved some cognitive and behavioral functions.   After discovering that Apolipoprotein E (ApoE), the main cholesterol carrier in the brain, facilitates clearance of beta amyloid, Landreth and his colleagues decided…

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Obama boosts Alzheimer’s funding by $130 million

By In the News

Kathleen Sebelius, Secretary of Health and Human Services, announced today that the Obama administration would increase funding for Alzheimer’s disease research by $130 million.   An extra $50 million will be made available immediately, and another $80 million will be added to the fiscal year 2013 federal budget to be released next week.  In total, this funding represents a 25% increase in funding for Alzheimer’s disease research over the next two years.  An additional $25 million will be allocated for caregiver support, provider education, public awareness, and improvements in data infrastructure.  “We can’t wait to confront the growing threat that Alzheimer’s…

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Aimee Pierce, M.D., Named Medical Director

By In the News

Dr. Aimee Pierce, Assistant Clinical Professor in UCI’s Department of Neurology, has been named Medical Director of the UCI MIND Memory Assessment Clinic.  Hailing from Eugene, Oregon, Dr. Pierce earned her B.S. in Biology at the California Institute of Technology in Pasadena, CA, and her M.D. at the Columbia College of Physicians and Surgeons.  After graduating she completed an internship in Internal Medicine at New York Presbyterian Hospital, a residency in neurology at UCLA, and a fellowship in geriatric neurology and dementia at the VA San Diego Healthcare System affiliated with UCSD.  Dr. Pierce officially joined the Department of Neurology…

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UCI MIND Launches MIND Matters Club

By In the News

On January 19, UCI MIND launched the MIND Matters Club at the home of Burton and Linda Young, who graciously hosted this inaugural gathering of individuals who have committed to  giving $1,906 or more annually to UCI MIND.  Guests gathered to hear Dr. Margaret Gatz, Professor of Psychology at the University of Southern California and Foreign Adjunct Professor at the Karolinska Institute in Stockholm, describe her research into dementia among Swedish twins.  Dr. Gatz and her colleagues followed Swedish twins across the past 25 years in order to identify differences between twin partners who developed dementia and those who did…

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Join us for the 3rd Annual ReMIND Emerging Scientists Symposium!

By In the News

The graduate student group ReMIND and the UCI MIND Institute will be hosting the Emerging Scientists Symposium on Neurological Disorders on February 9th at the University Club. It is a unique opportunity for graduate and postdoctoral researchers to present their work. Renowned Alzheimer’s disease researcher Dr. Li-Huei Tsai will give the keynote address. All are welcome to attend!  

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Watch our 2011 Alzheimer’s disease annual conference

By In the News

Please click on the following links to watch each of the presenters at our 2012 Alzheimer’s disease annual conference: 19th Annual Southern California Alzheimer’s Disease Research Conference When Does It Become Dementia? Transitioning from Healthy Aging to MCI and Dementia September 30, 2011 Welcome McGaugh – Making Lasting Memories Morris – Redefining Alzheimer’s Disease: The Danger of Revised Criteria for Mild Cognitive Impairment Kawas – Diagnosing Alzheimer’s Before Memory Loss Sets In: Proposed Research Criteria Snyder – When the Diagnosis is Early-Stage Alzheimer’s: What Happens Next? Tariot – Treating Dementia: A Look at Current and Future Medications Coon – Caregiving…

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19th Annual Southern California Alzheimer’s Disease Research Conference

By In the News

When Does It Become Dementia? Transitioning from Healthy Aging to MCI and Dementia September 30, 2011 at the Irvine Hilton, Irvine   The UCI Institute for Memory Impairments and Neurological Disorders (UCI MIND) at the University of California, Irvine, the Alzheimer’s Association Orange County Chapter, and Alzheimer’s Family Services Center are pleased to announce the 19th Annual Southern California Alzheimer’s Disease Research Conference, When Does It Become Dementia? Transitioning from Healthy Aging to MCI and Dementia.The conference will be held on Friday, September 30, 2011 at the Irvine Hilton located at 18800 MacArthur Blvd, Irvine. This year we anticipate over 450…

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Frontiers of the MIND 2011

By In the News

September 21, 2011, Frontiers of the MIND focusing on Traumatic Brain Injury Featuring Ann McKee, M.D. , Boston University Dr. McKee’s research interests center on the neuropathological alterations of neurodegenerative diseases, with a primary focus on the role of tau protein, axonal injury, trauma, vascular injury, and neurodegeneration. Much of her current work centers on the long-term consequences of repetitive head injury from contact sports and military service. As a board-certified neurologist and neuropathologist, she is particularly interested in the clinical, behavioral and psychological manifestations of pathological disease and the neuroanatomical localization of clinical symptoms. She has written widely on…

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Medications to avoid for patients

By In the News

Medications and Patients with Alzheimer’s Disease – What to Avoid Gaby T. Thai, M.D. Doctors are often asked whether there are any medications that someone with Alzheimer’s disease should avoid. Patients with Alzheimer’s disease may need medicines to treat symptoms of the disease, as well as for other health problems such as bladder incontinence, mood disturbances, high blood pressure, etc…  However, when a person takesmany medications, there is an increased risk of adverse effects, including confusion, mood swings, sleepiness, andworsening memory problems. Some medications can worsen symptoms of Alzheimer’s disease and should be avoided,if at all possible.   Sedatives and…

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Stress and its influence on Alzheimer’s disease

By In the News

Aging is an inevitable journey for everyone, and includes many obstacles and different paths to take.  How we live our lives can have enormous impact on whether we grow old gracefully, or succumb along the way. Good physical health, through diet and exercise, will allow people to remain active well into their twilight years, but as lifespan increases it is also important to take care of and maintain brain health as well.  Fortunately, it appears that what is good for the heart is also good for the brain, and thus by keeping active, both physically and mentally, and maintaining a…

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Plaque-blocking compound may aid Alzheimer’s treatment

By In the News

Researchers with the Institute for Memory Impairments and Neurological Disorders (UCI MIND) have discovered how a novel compound can reduce the accumulation of brain plaques seen in Alzheimer’s without the side effects produced by current drugs used for the chronic neurodegenerative disease. In a study published online in the Annals of Neurology, neurobiologists Kim Green and Frank LaFerla found that the ST101 compound triggers a process that carves up amyloid precursor proteins into benign molecules. These precursor proteins, when intact, ultimately can form into beta-amyloid plaques, which are the hallmark lesions of Alzheimer’s and believed to be the primary cause of dementia….

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Daily Pilot article on Wine for the MIND

By In the News

Bruce Cook, The Crowd: The mind is tops at wine event One American develops Alzheimer’s disease every 70 seconds, statistics report. According to Linda Scheck, who is with UC Irvine’s Mind Institute, the Baby Boomer generation is entering the high-risk age group for being diagnosed with the disease with as many as 10,000 turning 65 every day. Medical science is concerned that the possible onslaught of Alzheimer’s victims could become a national crisis in decades to come. In Orange County recently, the UCI Mind Institute, which focuses on memory impairment and neurological disorders, held a fundraiser called Saving Memories with…

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UCI MIND Scientists uncover presenilin function

By In the News

UCI MIND graduate student Kara Neely, and Professors Green and LaFerla have discovered a key role for presenilin, a protein involved in the production of amyloid-beta, which forms the plaques in Alzheimer’s disease.  In a study published in the February 23rd edition of the Journal of Neuroscience, the research team show that presenilin plays an integral role in the way that cells, including neurons, dispose of misfunctioning and broken proteins.  The accumulation of misfunctioning and broken proteins inside cells is thought to contribute to many neurodegenerative diseases, as well as to the aging process itself.  This research highlights an important…

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Wine for the Mind 2011 Photos

By In the News

Wine for the MIND – Saving Memories with Style attracted over 300 guests who enjoyed food, wine and fashion, all related to Alzheimer’s.  It was a fantastic event, chaired by Jacqueline DuPont and a committee of dedicated volunteers.   Below are a selection of the photos – click on the thumbnails to see the photos and cycle through them.  

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UCI MIND Seminar with Dr. Eric Reiman

By Community Events, In the News

Ending Alzheimer’s Together Eric M. Reiman, M.D. Banner Alzheimer’s Institute and Arizona Alzheimer’s Consortium Tuesday, January 18, 2011 – 7:30 p.m. Dr. Reiman will show how he and his colleagues have used brain imaging techniques to track Alzheimer’s disease decades before the onset of symptoms.  Also, he will describe their developing plan to find demonstrably effective Alzheimer’s prevention therapies as soon as possible. The seminar will be held at the Irvine Barclay Theatre (adjacent to the UCI campus) at 4242 Campus Drive, Irvine. Parking is provided in an adjacent structure for $8. The seminar is free of charge. No tickets or…

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Message from the Director

By In the News

Thank you for visiting the webpage of The Institute for Memory Impairments and Neurological Disorders. Your visit indicates a desire to learn more about Alzheimer’s disease and I hope you find this site useful and that it provides the information you are seeking. Right now, over 5.2 million Americans suffer from Alzheimer’s disease, including over 500,000 individuals in California and 30,000 in Orange County. Even more alarmingly, unless a way is found to delay the onset of Alzheimer’s disease, it is estimated that over 11 million people will suffer from this insidious disorder by the year 2050. The Institute is…

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Welcome to UCI MIND

By In the News

The Institute for Memory Impairments and Neurological Disorders (UCI MIND) at the University of California, Irvine is internationally recognized for its research accomplishments in disorders of the brain, particularly those that are age-related. The Institute is UCI’s center for aging and dementia research, with our faculty seeking to understand the causes leading to neurological disorders such as Alzheimer’s disease, frontotemporal dementia, Lewy body dementia, and Huntington’s disease. We aim to identify the life-style factors that promote wellness and “successful aging.” For those suffering from age-related memory problems, our goal is to diagnose disease, identify means for effectively treating it, and…

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