Role of inflammation in degeneration and regeneration of injured CNS; human CNS stem cell engraftment
Neuromuscular disorders, inclusion body myopathy, Paget disease, frontotemporal dementia, Prader Willi, morbid obesity, craniosynostosis
Alzheimer's disease, neurodegenerative diseases, myopathies, inflammation, microglia
Alzheimer’s disease; animal models, inclusion body myositis (IBM); Lewy body dementia; pre-clinical drug development; stem cell biology
survival analysis, analysis of high-dimensional brain image data, analysis of longitudinal data with change-points, terminal events, and variables subject to limit of detection.
Alzheimer’s disease, excitotoxicity, physiology of glutamate receptors, calcium and zinc dyshomeostasis, mitochondria, metabolomics, proteomics, fMRI investigation of cognitive decline in aging and Alzheimer’s disease.