Clinical Core

David Sultzer, MD, Professor, Psychiatry & Human Behavior, School of Medicine

Led by Dr. David Sultzer, the Clinical Core at the UCI Alzheimer’s Disease Research Center (ADRC) helps hundreds of families affected by Mild Cognitive Impairment (MCI), Alzheimer’s disease, and related disorders while gathering invaluable data on clinical presentation and progression of brain diseases for use by researchers.

Participants enrolled in the UCI ADRC Longitudinal Study undergo comprehensive annual evaluations that include a neurological and physical examination, neuropsychological assessment, brain imaging, lumbar puncture, blood and diagnostic tests, and an interview with a study partner (usually a close family member or friend).

Unless cultural or religious beliefs prohibit it, participants are also asked to consider brain donation upon death.  Data collected from participants is shared with Alzheimer’s disease investigators worldwide in a national database, the National Alzheimer’s Coordinating Center (NACC).


Sample of Core Publications